Invitrogen™ CIDEA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519908

Catalog No. PIPA519908

Description

In Western blot applications, this antibody detects a band at ~25kDa. A suggested positive control is mouse heart tissue lysate. PA5-19908 can be used with blocking peptide PEP-0034.

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Specifications

• Antigen: CIDEA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CIDEA
• Gene Alias: AW212747; cell death activator CIDE-A; Cell death-inducing DFFA-like effector A; cell death-inducing DNA fragmentation factor, alpha subunit-like effector A; cide a; Cidea; CIDE-A
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12683
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O70302
• Gene Symbols: CIDEA
• Immunogen: A peptide corresponding to amino acids 200 to 214 of mouse CIDE-A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov