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CIDEB Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 276001AP150UL

Encompass_Preferred

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Catalog No. 50-173-5714


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Description

Description

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.
Specifications

Specifications

CIDEB
Polyclonal
Unconjugated
CIDEB
Cell death activator CIDE B, CIDEB
Rabbit
Antigen Affinity Chromatography
RUO
27141
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9UHD4
CIDEB
CIDEB Fusion Protein Ag27003
150 μL
Primary
Human
Antibody
IgG
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