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Tocris Bioscience™ Ciliobrevin A

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Quantity:
5 mg
25 mg
Description
Ciliobrevin A is a Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Perturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.
Specifications
Specifications
Chemical Name or Material | 2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile |
CAS | 302803-72-1 |
Assay Percent Range | >98% |
Quantity | 5 mg |
Molecular Formula | C17H9Cl2N3O2 |
Formula Weight | Observed MW: 358.18 |
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