Cayman Chemical Ciprofloxacin (hydrochloride), 93107-08-5, 5 g

Supplier:  Cayman Chemical 142865

Molecular Formula C17H18FN3O3 • HCl, Purity ≥95%, Formula Weight 367.8, Synonyms: 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, monohydrochloride, BAY-o 9867, NSC 620634; A fluoroquinolone antibiotic; active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae, and H. pylori (MIC50s = 0.004-1 g/ml); active against clinical isolates of Bacteroides, Fusobacterium, Eubacterium, Actinomyces, Peptococcus, Peptostreptococcus, and Streptococcus in vitro (MIC50s = 0.5-2 g/ml); inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 13.5 and 5.76 g/ml, respectively); reduces mortality in mouse models of intraperitoneal E. coli, P. vulgaris, K. pneumoniae, P. aeruginosa, and S. aureus infection (ED90-100s = 1-5, 2.5-5, 5-10, 20-40, and 80 mg/kg, respectively); prevents mortality in a mouse model of subcutaneous S. typhimurium infection at 10 mg/kg.

Catalog No. NC1508769