Invitrogen™ CIRBP Recombinant Rabbit Monoclonal Antibody (3V9S7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537911

Catalog No. PIMA537911

Description

Positive Samples: 293T, HepG2, SH-SY5Y Immunogen sequence: MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD RGYGGNRFES RSGGYGGSRD YYSSRSQSGG YSDRSSGGSY RDSYDSYATH NE.

CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.

Specifications

• Antigen: CIRBP
• Classification: Recombinant Monoclonal
• Concentration: 0.8 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P60824, P60825, Q14011
• Gene Symbols: CIRBP
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (Q14011).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 3V9S7
• Conjugate: Unconjugated
• Gene: CIRBP
• Gene Alias: A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA binding protein; glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1153, 12696, 81825
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov