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cis-4-Hydroxy-L-proline, 99%

Catalog No. AAH27194MD
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250 mg
1 g
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AAH27194MD 250 mg
AAH2719403 1 g
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Catalog No. AAH27194MD Supplier Thermo Scientific Chemicals Supplier No. H27194MD
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Description

CAS: 618-27-9 | C5H9NO3 | 131.13 g/mol

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 618-27-9
Molecular Formula C5H9NO3
Molecular Weight (g/mol) 131.13
MDL Number MFCD00064319,MFCD00064320
InChI Key PMMYEEVYMWASQN-IMJSIDKUSA-N
Synonym cis-4-hydroxy-l-proline, 2s,4s-4-hydroxypyrrolidine-2-carboxylic acid, l-hydroxyproline, l-allohydroxyproline, allo-4-hydroxy-l-proline, cis-4-hydroxyproline, 4s-4-hydroxy-l-proline, l-cis-4-hydroxyproline, l-allo-hydroxyproline, l-proline, 4-hydroxy-, 4s
PubChem CID 440015
ChEBI CHEBI:28397
IUPAC Name (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid
SMILES O[C@@H]1CN[C@@H](C1)C(O)=O

Specifications

Melting Point ∽250°C (decomposition)
Solubility Information Soluble in water.
Quantity 250 mg
Formula Weight 131.13
Optical Rotation −59° (c=2 in Water)
Percent Purity 99%
Chemical Name or Material cis-4-Hydroxy-L-proline

Safety and Handling

EINECSNumber 210-542-1
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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