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cis-Ned 19, Tocris Bioscience™

Catalog No. 395310
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10 mg
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Catalog No. Quantity
39-531-0 10 mg
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Catalog No. 39-531-0 Supplier R&D Systems Supplier No. 3953/10
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Description

NAADP antagonist; inhibits Ca2+ release

Irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist; inhibits Ca2+ release (IC50 = 800 nM) and [32P]NAADP binding (IC50 = 15 μM). Stereoisomer of trans-Ned 19 . Fluorescently labels NAADP receptors in intact cells (excitation 351 and 365 nm using an ultraviolet Argon laser).

Isomer of trans-Ned 19 .

Chemical Identifiers

CAS 1137264-00-6
Molecular Formula C30H31FN4O3
Molecular Weight (g/mol) 514.601
InChI Key FUHCEERDBRGPQZ-LSYYVWMOSA-N
Synonym cis-ned 19, 1s,3s-1-3-4-2-fluorophenyl piperazin-1-yl methyl-4-methoxyphenyl-2,3,4,9-tetrahydro-1h-pyrido 3,4-b indole-3-carboxylic acid
PubChem CID 1427626
IUPAC Name (1S,3S)-1-[3-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
SMILES COC1=C(C=C(C=C1)C2C3=C(CC(N2)C(=O)O)C4=CC=CC=C4N3)CN5CCN(CC5)C6=CC=CC=C6F

Specifications

Quantity 10 mg
Formula Weight 514.59
Percent Purity >98%
Chemical Name or Material cis-Ned 19

Safety and Handling

Recommended Storage Store at -20°C
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