CKMT1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-0164	150 μL

Catalog No. 50-173-0164 Supplier Proteintech Group Inc Supplier No. 153461AP150UL

Description

Rabbit Polyclonal Antibody

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many maligt cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.

Specifications

• Antigen: CKMT1A
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.38 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CKMT1A
• Gene Accession No.: P12532
• Gene Alias: c, CKMiMi, CKMT, CKMT1, CKMT1A, Mia CK, U MtCK
• Gene Symbols: CKMT1A
• Host Species: Rabbit
• Immunogen: CKMT1A Fusion Protein Ag7583
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 548596
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG