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Tocris Bioscience™ Cladribine

Catalog No. 529250
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Catalog No. Quantity
52-925-0 50 mg
52-921-0 10 mg
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Catalog No. 52-925-0 Supplier Tocris Bioscience™ Supplier No. 5292/50
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Description

Deoxyadenosine analog; pro-apoptotic

Cladribine is an adenosine deaminase (ADA)-resistant analog of deoxyadenosine. Exhibits anti-leukemic activity; Inhibits cell growth of lymphoid and myeloid neoplasm (IC50 = 20 - 87 nM). Pro-apoptotic; induces DNA double-strand breaks. Also inhibits ribonuclease reductase (IC50 = 0.11 - 0.28 μM). Displays activity in vitro and in vivo. Orally bioavailable.

Specifications

Purity >99%
Quantity 50 mg
Product Type Cladribine
Molecular Weight (g/mol) 285.69
Inhibitors Cladribine

For Research Use Only

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