Invitrogen™ Claudin 10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
01-673-307	Invitrogen™ PA137476	1 mL
PIPA532351	Invitrogen™ PA532351	500 μL

Description

This antibody is predicted to react with bovine, canine, and mouse based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is brain, skeletal muscle or ovarian carcinoma.

Claudin proteins are a family of proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Specifications

• Antigen: Claudin 10
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.6
• Gene Accession No.: P78369
• Gene ID (Entrez): 9071
• Immunogen: Synthetic peptide from C-terminus of human claudin-10 protein.
• Product Type: Antibody

• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: Cldn10
• Gene Alias: 6720456I16Rik; claudin 10; claudin 10A; claudin 10B; claudin-10; claudin-10A; Cldn10; Cldn10a; Cldn10b; CPETRL3; D14Ertd728e; Oligodendrocyte-specific protein-like; OSP-L; OSP-like; OSP-like protein
• Gene Symbols: Cldn10
• Primary or Secondary: Primary
• Purification Method: Antigen Affinity Chromatography