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Invitrogen™ Claudin 19 Polyclonal Antibody
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Catalog No. PIPA540751
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100 μL
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PIPA540751 100 μL
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Catalog No. PIPA540751 Supplier Invitrogen™ Supplier No. PA540751
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Description

Rabbit Polyclonal Antibody

Peptide sequence: AVLGGSFLCC TCPEPERPNS SPQPYRPGPS AAAREPVVKL PASAKGPLGV Sequence homology: Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 100%; Rat: 93%.

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 19
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CLDN19
Gene Accession No. Q8N6F1
Gene Alias claudin 19; claudin-19; Cldn19; HOMG5
Gene Symbols CLDN19
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human CLDN19 (aa 175-224).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149461
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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