Claudin 3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA532353

Catalog No. PIPA532353

Description

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is small intestine tissue.

Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of a network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different claudin composition.

Specifications

• Antigen: Claudin 3
• Classification: Polyclonal
• Gene: CLDN3
• Gene Alias: C7orf1, CPE-R2, CPETR2, HRVP1, RVP1, CPE-R 2, CPE-receptor 2, Clostridium perfringens enterotoxin receptor 2, claudin-3, ventral prostate.1 protein homolog, ventral prostate.1-like protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1365, 65130, 12739
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Gene Accession No.: Q63400, Q9Z0G9, O15551
• Gene Symbols: CLDN3
• Immunogen: Synthetic peptide derived from the C-terminus of mouse Claudin-3
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Chicken, Human, Mouse, Pig, Rat
• Product Type: Antibody
• Isotype: IgG