Invitrogen™ Claudin 6 Monoclonal Antibody (342927)

Catalog No.	Quantity
PIMA524076	100 μg

Catalog No. PIMA524076 Supplier Invitrogen™ Supplier No. MA524076

Description

Mouse Monoclonal Antibody

This antibody stains human Claudin-6 transfected cells but not irrelevant transfectants. Reconstitute at 0.5 mg/mL in sterile PBS.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Specifications

• Antigen: Claudin 6
• Applications: Flow Cytometry, Immunocytochemistry
• Classification: Monoclonal
• Clone: 342927
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: CLDN6
• Gene Accession No.: P56747
• Gene Alias: AL024037; claudin 6; Claudin6; claudin-6; CLD6; CLDN6; Skullin; tight junction molecule claudin 6; UNQ757/PRO1488
• Gene Symbols: CLDN6
• Host Species: Mouse
• Immunogen: NS0 mouse myeloma cell line transfected with human Claudin-6 Met1-Val220.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9074
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b