Invitrogen™ Claudin 7 Monoclonal Antibody (5D10F3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 374800

Catalog No. 37-480-0

Description

Claudin 7 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), IP, ELISA

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.

Specifications

• Antigen: Claudin 7
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: O95471, Q9Z261
• Gene Symbols: CLDN7
• Immunogen: Synthetic peptide derived from the C-terminal region of the human claudin-7 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 5D10F3
• Conjugate: Unconjugated
• Gene: CLDN7
• Gene Alias: CEPTRL2; claudin 7; claudin-1; Claudin-7; Cldn7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; Hs.84359
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1366, 53624
• Content And Storage: -20°C
• Form: Liquid