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Invitrogen™ Claudin 7 Polyclonal Antibody

Catalog No. 01673305
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500 μL
1 mL
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01-673-305 1 mL
PIPA532356 500 μL
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Catalog No. 01-673-305 Supplier Invitrogen™ Supplier No. PA137474
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is colon carcinoma.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.12 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene CLDN7
Gene Accession No. O95471, Q9Z1L1, Q9Z261
Gene Alias CEPTRL2; claudin 7; claudin-1; Claudin-7; Cldn7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; Hs.84359
Gene Symbols CLDN7
Host Species Rabbit
Immunogen Synthetic peptide from C-terminus of human claudin 7 protein.
Purification Method Antigen Affinity Chromatography
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1366, 53624, 65132
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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