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Invitrogen™ Claudin 7 Polyclonal Antibody
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Catalog No. PIPA596042
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PIPA596042 100 μL
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Catalog No. PIPA596042 Supplier Invitrogen™ Supplier No. PA596042
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QWQMSSYAGD NIITAQAMYK GLWMDCVTQS TGMMSCKMYD SVLALSAALQ ATRALMVVSL VLGFLAMFVA TMGMKCTRCG GDDKVKKARI AMGGGIIFIV AGLAALVACS WYGHQIVTDF YNPLIPTNIK YEFGPAIFIG WAGSALVILG GALLSCSCPG NESKAGYRVP RSYPKSNSSK EYV; Positive Samples: MCF7, HT-29, A-549, HO-8910PM, Mouse lung, Mouse kidney, Mouse liver, rat kidney, rat liver; Cellular Location: Cell junction, Cell membrane, Lateral cell membrane, Multi-pass membrane protein, tight junction.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 7
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.73 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CLDN7
Gene Accession No. O95471, Q9Z1L1, Q9Z261
Gene Alias CEPTRL2; claudin 7; claudin-1; Claudin-7; Cldn7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; Hs.84359
Gene Symbols CLDN7
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7 (NP_0012983).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1366, 53624, 65132
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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