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Invitrogen™ CLCN7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577054

Catalog No. PIPA577054


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Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CLCN7
Polyclonal
Unconjugated
CLCN7
AA409691; AW538136; chloride channel 7; chloride channel 7 alpha subunit; Chloride channel protein 7; chloride channel, voltage-sensitive 7; chloride voltage-gated channel 7; CLC7; CLC-7; CLCN7; CLCN-7; D17Wsu51e; H(+)/Cl(-) exchange transporter 7; OPTA2; OPTB4; PPP1R63; protein phosphatase 1, regulatory subunit 63
Rabbit
Antigen affinity chromatography
RUO
1186, 26373, 29233
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide
O70496, P51798, P51799
CLCN7
Recombinant full length Human CLCN7.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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