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Invitrogen™ CLEC12A Polyclonal Antibody
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Catalog No. PIPA5120980
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100 μL
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PIPA5120980 100 μL
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Catalog No. PIPA5120980 Supplier Invitrogen™ Supplier No. PA5120980
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Description

Rabbit Polyclonal Antibody

Positive test controls include: K-562. The target is usually found in the following locations: Cell membrane, Single-pass type II membrane protein. Immunogen sequence: VTLKIEMKKM NKLQNISEEL QRNISLQLMS NMNISNKIRN LSTTLQTIAT KLCRELYSKE QEHKCKPCPR RWIWHKDSCY FLSDDVQTWQ ESKMACAAQN ASLLKINNKN ALEFIKSQSR SYDYWLGLSP EEDSTRGMRV DNIINSSAWV IRNAPDLNNM YCGYINRLYV QYYHCTYKKR MICEKMANPV QLGSTYFREA.

CD371 is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLEC12A
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.40 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CLEC12A
Gene Accession No. Q504P2, Q5QGZ9
Gene Alias CD371; Clec12a; CLL1; CLL-1; C-type lectin domain family 12 member A; C-type lectin domain family 12, member A; C-type lectin protein CLL-1; C-type lectin-like molecule 1; C-type lectin-like molecule-1; D230024O04; DCAL2; DCAL-2; Dendritic cell-associated lectin 2; KLRL1; Micl; Myeloid inhibitory C-type lectin-like receptor
Gene Symbols CLEC12A
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 160364, 232413, 680338
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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