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Invitrogen™ CLEC5A Polyclonal Antibody

Catalog No. PIPA534928
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100 μL
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PIPA534928 100 μL
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Catalog No. PIPA534928 Supplier Invitrogen™ Supplier No. PA534928

Rabbit Polyclonal Antibody

Recommended positive controls: K562. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLEC5A
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene CLEC5A
Gene Accession No. Q9NY25, Q9R007
Gene Alias CLEC5A; Clecsf5; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin domain family 5, member a; C-type lectin superfamily member 5; Ly100; Mdl1; MDL-1; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; type II transmembrane protein MDL-1
Gene Symbols CLEC5A
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human CLEC5A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23601, 23845
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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