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Invitrogen™ CLEC9A Polyclonal Antibody
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Catalog No. PIPA5112113
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PIPA5112113 100 μL
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Catalog No. PIPA5112113 Supplier Invitrogen™ Supplier No. PA5112113
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Description

Rabbit Polyclonal Antibody

CLEC9A Polyclonal Antibody for Western Blot

C-type lectin domain family 9 member A (CLEC9A) is a gene located on chromosome 12p13.2, encoding a protein that belongs to the C-type lectin receptor family. CLEC9A is primarily expressed on dendritic cells and certain subsets of macrophages, playing a pivotal role in the immune system by recognizing and binding dead cell debris, including necrotic cells. This receptor facilitates the presentation of antigens derived from dead cells to T cells, thus contributing to the initiation of immune responses. CLEC9A is involved in cross-presentation, a process crucial for adaptive immunity, particularly in the context of viral infections and cancer. Its expression and activity are of particular interest for vaccine development and immunotherapy, given its ability to enhance antigen presentation and stimulate robust immune responses. Research into CLEC9A continues to explore its therapeutic potential for modulating immune activity in various diseases, including cancer and infectious diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLEC9A
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CLEC9A
Gene Accession No. Q6UXN8
Gene Alias 9830005G06Rik; CD370; Clec9a; C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; Dendritic cell natural killer lectin group receptor 1; DNGR1; DNGR-1; HEEE9341; RGD1562513; UNQ9341; UNQ9341/PRO34046
Gene Symbols CLEC9A
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the N-terminus of the Human DNGR-1/CLEC9A.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283420
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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