Invitrogen™ CLNS1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101663

Catalog No. PIPA5101663

Description

Antibody detects endogenous levels of total CLNS1A.

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.

Specifications

• Antigen: CLNS1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLNS1A
• Gene Alias: 2610036D06Rik; 2610100O04Rik; ARPC1A; chloride channel; chloride channel current inducer; chloride channel regulator; chloride channel regulatory protein; chloride channel, nucleotide sensitive 1A; chloride channel, nucleotide-sensitive, 1A; chloride conductance regulatory protein ICln; Chloride ion current inducer protein; chloride nucleotide-sensitive channel 1A; ClCI; Clcni; Clns 1a; CLNS1A; CLNS1B; I(Cln); icln; icln protein; methylosome subunit pICln; pIcIn; pICln; Rcl1; Reticulocyte pICln; reticulocyte protein ICln; SOP2L; SOP2-like protein; swelling dependent chloride channel; swelling-induced chloride conductance regulatory protein; swelling-induced chloride conductance regulatory protein pIcIn
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1207
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P54105
• Gene Symbols: CLNS1A
• Immunogen: A synthesized peptide derived from human CLNS1A(Accession P54105), corresponding to amino acid residues A183-A233.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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