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Clofazimine, G-Biosciences
SCI_ED

Catalog No. S932454
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Quantity:
5 g

Description

lofazimine is an active phenazine composed of an imino group and aromatic tricyclic heterocycles that is used as an antimycobacterial, anti-inflammatory and anti-cancer compound.

lofazimine is an active phenazine composed of an imino group and aromatic tricyclic heterocycles that is used as an antimycobacterial, anti-inflammatory and anti-cancer compound. It has been shown to be a potent in vivo antimycobacterial agent toward Mycobacterium leprae and in vitro to Mycobacterium avium.

As an anti-inflammatory, clofazimine inhibits reactive oxygen species (ROS) formation within neutrophils by inhibiting myeloperoxidase catalyzed reactions. The formed ROS are responsible for activating tumor necrosis factor alpha and interleukin 8 (IL8), which are inflammatory cytokines.

Chemical Identifiers

Molecular Weight (g/mol) 473.40 g/mol

Specifications

Boiling Point 210 to 212°C
Quantity 5 g
Percent Purity 98%
Grade Laboratory
Physical Form Powder
Product Line Gibco
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