Clofibrate, 95+%

Catalog No.	Quantity
AAJ6034222	100 g
AAJ6034203	1 g
AAJ6034206	5 g
AAJ6034214	25 g

Catalog No. AAJ6034222 Supplier Thermo Scientific Chemicals Supplier No. J6034222

Description

CAS: 637-07-0 | C12H15ClO3 | 242.70 g/mol

It is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well. Clofibrate is a ligand agonist for PPARα (peroxisome proliferator-activated receptor α), or an inducer of cytochromes P450’s CYP4A1 and CYP4A3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble to 100 mM in DMSO.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, bases. Store in refrigerator.

Specifications

Chemical Identifiers

• CAS: 637-07-0
• Molecular Formula: C12H15ClO3
• Molecular Weight (g/mol): 242.70
• MDL Number: MFCD00000615
• InChI Key: KNHUKKLJHYUCFP-UHFFFAOYSA-N
• Synonym: clofibrate, ethyl clofibrate, clofibratum, clofibrato, atromid-s, miscleron, atromid, liprin, epib, angiokapsul
• PubChem CID: 2796
• ChEBI: CHEBI:3750
• IUPAC Name: ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
• SMILES: CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1

• Density: 1.14
• Boiling Point: 154°C to 156°C
• Flash Point: 113°C (235°F)
• Refractive Index: 1.5
• Quantity: 100 g
• UN Number: UN3082
• Beilstein: 1913459
• Merck Index: 14,2377
• Solubility Information: Soluble to 100 mM in DMSO.
• Formula Weight: 242.7
• Percent Purity: ≥95%
• Physical Form: Liquid
• Chemical Name or Material: Clofibrate

Safety and Handling

Hazard Category	H302-H315-H318-H335
Hazard Statement	GHS H Statement H318-H302-H335-H315 Causes serious eye damage. Harmful if swallowed. May cause respiratory irritation. Causes skin irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c
DOTInformation	Transport Hazard Class: 9; Packing Group: III; Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
EINECSNumber	211-277-4
RTECSNumber	UE9480000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only