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Selleck Chemical LLC CM272 5mg

Supplier: Selleck Chemical LLC S88125MG

CM-272 is a novel first-in-class dual reversible inhibitor ofG9a (GLP) andDNMTs with IC50 of 8?nM, 382 nM, 85 nM, 1200 nM, 2?nM forG9a,DNMT1,DNMT3A,DNMT3B,GLP, respectively. CM-272 prolongs survival in in vivo models of haematological malignancies by at least in part inducing immunogenic cell death. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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