Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. CNOT1 Mouse anti-Human, Clone: 1A10A11, Proteintech 

CNOT1 Mouse anti-Human, Clone: 1A10A11, Proteintech
SDP

Catalog No. 501736929 Shop All Proteintech Group Inc Products
Encompass_Preferred
Change view
Click to view available options
Quantity:
150 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-173-6929 150 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 50-173-6929 Supplier Proteintech Group Inc Supplier No. 665071IG150UL
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

This is a rabbit polyclonal antibody raised against a region from the C-terminal CNOT1 of human origin. CNOT1 exists as many isoforms. Isoform one is about 267 kDa and isoform four is about 173 kDa.

Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3′UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintece of emryonic stem (ES) cell identity.

Specifications

Antigen CNOT1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1A10A11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CNOT1
Gene Accession No. A5YKK6
Gene Alias AD 005, CCR4 associated factor 1, CDC39, CNOT1, hNOT1, KIAA1007, NOT1, NOT1H
Gene Symbols CNOT1
Host Species Mouse
Immunogen CNOT1 Fusion Protein Ag5623
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23019
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.