Invitrogen™ CNTF Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA19521

Catalog No. 01-674-404

Description

PA1-9521 detects CNTF in human, mouse and rat samples. PA1-9521 has been successfully used in Western blot, ELISA,and immunohistochemistry procedures. By Western blot, PA1-9521 detects a 23 kDa protein representing CNTF. PA1-9521 immunogen is a synthetic peptide based on the human CNTF protein. Store at 4ºC for up to 1 week, and -20ºC as undiluted liquid long-term.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Specifications

• Antigen: CNTF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CNTF
• Gene Alias: AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
• Host Species: Chicken
• Purification Method: IgY Fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 1270, 12803, 25707
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P20294, P26441, P51642
• Gene Symbols: CNTF
• Immunogen: Synthetic peptide based on the human CNTF protein.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY