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Invitrogen™ CNTF Polyclonal Antibody
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Catalog No. 01674404
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500 μg
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Catalog No. Quantity
01-674-404 500 μg
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Catalog No. 01-674-404 Supplier Invitrogen™ Supplier No. PA19521
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Description

Chicken Polyclonal Antibody

PA1-9521 detects CNTF in human, mouse and rat samples. PA1-9521 has been successfully used in Western blot, ELISA,and immunohistochemistry procedures. By Western blot, PA1-9521 detects a 23 kDa protein representing CNTF. PA1-9521 immunogen is a synthetic peptide based on the human CNTF protein. Store at 4°C for up to 1 week, and -20°C as undiluted liquid long-term.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
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Specifications

Antigen CNTF
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CNTF
Gene Accession No. P20294, P26441, P51642
Gene Alias AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
Gene Symbols CNTF
Host Species Chicken
Immunogen Synthetic peptide based on the human CNTF protein.
Purification Method IgY fraction
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1270, 12803, 25707
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
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