Invitrogen™ CNTNAP1 Polyclonal Antibody

Catalog No.	Quantity
PIPA542737	100 μL

Catalog No. PIPA542737 Supplier Invitrogen™ Supplier No. PA542737

Description

Rabbit Polyclonal Antibody

Peptide sequence: LQIDLMKKHR IRAVATQGSF NSWDWVTRYM LLYGDRVDSW TPFYQRGHNS Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%.

CNTNAP1 was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex. The 1, 384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein, ' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. The gene product was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex. The 1, 381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein, ' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Specifications

• Antigen: CNTNAP1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene: Cntnap1
• Gene Accession No.: P78357
• Gene Alias: AI841080; Caspr; caspr1; CNTNAP; CNTNAP1; contactin associated protein 1; contactin associated protein-like 1; contactin-associated protein 1; LOW QUALITY PROTEIN: contactin-associated protein 1; MHDNIV; NCP1; neurexin 4; neurexin 4 (contactin associated protein); neurexin IV; Neurexin-4; NRXN4; p190; paranodin; shm
• Gene Symbols: Cntnap1
• Host Species: Rabbit
• Immunogen: Synthetic peptide directed towards the N-terminal of human CNTNAP1 (aa 72-121).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8506
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG