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Invitrogen™ Cofilin Monoclonal Antibody (GT567)
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Catalog No. PIMA517275
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100 μL
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Catalog No. Quantity
PIMA517275 100 μL
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Catalog No. PIMA517275 Supplier Invitrogen™ Supplier No. MA517275
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Description

Mouse Monoclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, A375, Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2. Predicted reactivity: Mouse (98%), Rat (99%), Pig (99%), Sheep (99%), Rhesus Monkey (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cofilin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT567
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CFL1
Gene Accession No. P18760, P23528, P45592
Gene Alias 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Gene Symbols CFL1
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human Cofilin 1. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1072, 12631, 29271
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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