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Description
Antibody detects endogenous levels of total Endostatin.
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.
Specifications
Specifications
| Antigen | COL15A1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide |
| Gene | COL15A1 |
| Gene Accession No. | O35206, P39059 |
| Gene Alias | COFA1; COL15A1; Collagen alpha-1(XV) chain; collagen type XV alpha 1 chain; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide; collagen, type XV, alpha 1; endostatin-XV; procollagen type XV; procollagen, type XV; Related to endostatin; Restin; Restin-2; Restin-3; Restin-4; Restin-I; Restin-II; Restin-III; Restin-IV; type XV collagen |
| Gene Symbols | COL15A1 |
| Show More |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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