Invitrogen™ Procollagen I C-Peptide Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535380

Catalog No. PIPA535380

Description

This antibody is predicted to react with most mammals, birds and amphibians based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots. Titrated for consistent results in Western Blot and IHC applications.

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum depends on age and sex.

Specifications

• Antigen: Procollagen I C-Peptide
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL1A1
• Gene Alias: Alpha-1 type I collagen; alpha1(I) procollagen; COL1A1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain; collagen type I alpha 1; collagen, type I, alpha 1; C-terminal Collagen; EDSC; OI1; OI2; OI3; OI4; PICP; pro-alpha-1 collagen type 1; Procol; Procollagen; type I proalpha 1; type I procollagen alpha 1 chain
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1277, 12842, 29393, 443483
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P02452, P02454, P11087
• Gene Symbols: COL1A1
• Immunogen: Synthetic peptide corresponding to amino acid residues specific to the C-terminal region of human collagen 1, alpha 1 telopeptide conjugated to KLH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Sheep
• Product Type: Antibody
• Isotype: IgG