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Invitrogen™ COL1A2 Recombinant Rabbit Monoclonal Antibody (5U8R0)
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Catalog No. FEMA551421
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FEMA551421 100 μL
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Catalog No. FEMA551421 Supplier Invitrogen™ Supplier No. MA551421
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Description

Rabbit Recombinant Monoclonal Antibody

COL1A2 Recombinant Monoclonal Antibody for ELISA, ICC/IF, Western Blot

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL1A2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 5U8R0
Concentration 1.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene COL1A2
Gene Accession No. P08123, Q01149
Gene Alias AA960264; AI325291; alpha 2 type I procollagen; alpha 2(I) collagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha2 chain of type I collagen; alpha-2 type I collagen; alpha-2(1) collagen; COL1; COL1A2; Col1a-2; COLA; Cola2; Cola-2; collagen; collagen a2; collagen alpha 2(I) chain precursor; collagen alpha-2; collagen alpha-2 chain precursor; collagen alpha-2(I) chain; collagen COL1A2; Collagen I; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 2 chain; collagen, type I, alpha 2; OI4; oim; osteogenesis imperfecta; precollagen alpha-2; procollagen, type I, alpha 2; type I collagen alpha-2 chain; type I procollagen
Gene Symbols COL1A2
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1278, 12843
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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