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Invitrogen™ COL22A1 Polyclonal Antibody
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Catalog No. PIPA555200
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100 μL
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PIPA555200 100 μL
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Catalog No. PIPA555200 Supplier Invitrogen™ Supplier No. PA555200
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKEELEEIAS EPKSAHVFHV SDFNAIDKIR GKLRRRLCEN VLCPSVRVEG DRFKHTNGGT KEITGFDLMD LFSVKEILGK RENGAQSSYV RMG Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL22A1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COL22A1
Gene Accession No. Q8NFW1
Gene Alias 2310067L16Rik; C80743; COL22A1; Collagen alpha-1(XXII) chain; collagen type XXII alpha 1; collagen type XXII alpha 1 chain; collagen, type XXII, alpha 1; procollagen, type XXII, alpha 1
Gene Symbols COL22A1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COL22A1. Recombinant protein control fragment (Product #RP-93895).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 169044
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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