Invitrogen™ COL7A1 Monoclonal Antibody (LH7.2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA513432

Catalog No. PIMA513432

Description

MA5-13432 targets Collagen VII in IF, IHC (F), and IM applications and shows reactivity with Bovine, Guinea Pig, Goat, Human, Non-human primate, Ovine, and Porcine samples. The MA5-13432 immunogen is insoluble fractions of human neonatal foreskin epidermal cells.

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: COL7A1
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q02388
• Gene Symbols: COL7A1
• Immunogen: Insoluble fractions of human neonatal foreskin epidermal cells.
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Bovine, Sheep, Pig, Guinea Pig, Goat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Frozen), Immunomicroscopy
• Clone: LH7.2
• Conjugate: Unconjugated
• Gene: COL7A1
• Gene Alias: alpha-1 type VII collagen; AW209154; COL7A1; collagen alpha-1(VII) chain; collagen type VII alpha 1; collagen type VII alpha 1 chain; collagen vii; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; EBD1; EBDCT; EBR1; HGNC:2214; LC collagen; long chain collagen; long-chain collagen; NDNC8; procollagen, type VII, alpha 1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 100523209, 100726045, 101119261, 106503435, 1294, 507133
• Content And Storage: 4°C
• Form: Liquid