Invitrogen™ Collagen III Monoclonal Antibody (FH-7A)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA122147

Catalog No. PIMA122147

Description

Recommended positive controls: human skin. MA1-22147 specifically recognizes native and denatured collagen type III in human and rat samples. It does not recognize collagen types I, II, IV, V, VI and X. By Western blot, this antibody detects a ~70 kDa band in reduced denatured samples, and a ~300 kDa band in non-reduced, non-denatured samples. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.

Specifications

• Antigen: Collagen III
• Classification: Monoclonal
• Concentration: 4 mg/mL
• Formulation: Ascites with 15mM sodium azide
• Gene Accession No.: P02461, P13941
• Gene Symbols: Col3a1
• Immunogen: Human collagen type III protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 100009177, 1281, 84032
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Dot Blot, ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: FH-7A
• Conjugate: Unconjugated
• Gene: Col3a1
• Gene Alias: alpha1 (III) collagen; alpha-1 collagen type III; alpha-1 type III collagen; alpha-1 type-3 collagen; AW550625; COL 3; COL3; COL3 alpha 1; COL3A1; Col3a-1; collagen; Collagen 3; collagen alpha 1 type III; collagen alpha-1(III) chain; collagen type III alpha 1 chain; collagen, fetal; collagen, type III, alpha 1; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant); collagen, type III, alpha 1 chain, fibril forming; Collagen3; EDS4A; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; mKIAA4231; MMS10-W; Ms10w; PIIINP; pro alpha 1 type III collagen; procollagen, type III, alpha 1; unknown
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Rabbit
• Product Type: Antibody
• Isotype: IgG1