Invitrogen™ Collagen V Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102416

Catalog No. PIPA5102416

Description

Antibody detects endogenous levels of total Collagen V alpha 1.

COL5A1 encodes an alpha chain for one of the lowabundance fibrillar collagens. Fibrillar collagen molecules aretrimers that can be composed of one or more types of alpha chains.Type V collagen is found in tissues containing type I collagen andappears to regulate the assembly of heterotypic fibers composed ofboth type I and type V collagen. COL5A1 product is closelyrelated to type XI collagen and it is possible that the collagenchains of types V and XI constitute a single collagen type withtissue-specific chain combinations. Mutations in this gene areassociated with Ehlers-Danlos syndrome, types I and II.

Specifications

• Antigen: Collagen V
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O88207, P20908, Q9JI03
• Gene Symbols: COL5A1
• Immunogen: A synthesized peptide derived from human COL5A1(Accession P20908), corresponding to amino acid residues E305-L355.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Dilution:
  Western Blot (WB)  1:500-1:2,000
  Immunohistochemistry (Paraffin) (IHC (P))  1:50-1:200
  Immunocytochemistry (ICC/IF)  1:100-1:500
• Gene: COL5A1
• Gene Alias: AB collagen; AI413331; alpha-1 type V collagen; alpha1(V) collagen; COL5; Col5a1; Collagen 5; collagen alpha 1 (V); collagen alpha-1(V) chain; collagen type 5 alpha 1; collagen type V alpha 1; collagen type V alpha 1 chain; collagen, type V, alpha 1; EDSC; pro-alpha1(V) collagen; procollagen alpha 1(V); procollagen type V alpha 1; procollagen, type V, alpha 1; RP11-263F14.1; Type V Collagen
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12831, 1289, 85490
• Content And Storage: -20°C
• Form: Liquid