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  6. Invitrogen™ Collagen X Monoclonal Antibody (X53), eBioscience™, Invitrogen™ 

Invitrogen™ Collagen X Monoclonal Antibody (X53), eBioscience™, Invitrogen™
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Catalog No. 501122854
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50-112-2854 100 μg
50-112-2853 25 μg
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Catalog No. 50-112-2854 Supplier Invitrogen™ Supplier No. 14977182
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Description

Mouse Monoclonal Antibody

Description: The monoclonal antibody X53 recognizes human, mouse, porcine, guinea pig, and rat Collagen Type X. X53 does not cross-react with collagen types I, II, III, IV, or VI. Collagen Type X is a homotrimeric short chain collagen. Collagen Type X has limited expression in normal adult tissues, primarily being expressed during bone growth and development. Expression is localized to the peri- and extracellular matrix of hypertrophic chondrocytes during endochondral ossification and also plays a role in cartilage mineralization. Collagen Type X is elevated in many tumor types with expression being localized in the vasculature. Mutations to the gene COL10A1, which encodes human Collagen Type X, is associated with Schmid type metaphyseal chondrodysplasia. Applications Reported: This X53 antibody has been reported for use in microscopy, immunohistochemical staining, ELISA, and immunocytochemistry. Applications Tested: This X53 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Collagen X
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone X53
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene COL10A1
Gene Accession No. Q03692, Q05306
Gene Alias Col10; COL10A1; Col10a-1; Collagen alpha-1(X) chain; collagen type X alpha 1 chain; collagen X, alpha-1 polypeptide; collagen, type X, alpha 1; collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia); pro alpha 1; procollagen, type X, alpha 1; Schmid metaphyseal chondrodysplasia; type X collagen; type X collagen, alpha 1
Gene Symbols COL10A1
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100856711, 106026924, 12813, 1300, 25681, 448809
Target Species Human, Mouse, Rat, Canine, Pig, Guinea Pig
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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