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Invitrogen™ COMP Polyclonal Antibody
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Catalog No. PIPA595547
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100 μg
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PIPA595547 100 μg
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Catalog No. PIPA595547 Supplier Invitrogen™ Supplier No. PA595547
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell, human Hacat whole cell, human CACO-2 whole cell, human 293T whole cell, rat cartilage tissue, mouse cartilage tissue. IHC: mouse knee-joint tissue, rat knee-joint tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
TRUSTED_SUSTAINABILITY

Specifications

Antigen COMP
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene COMP
Gene Accession No. P35444, P49747, Q9R0G6
Gene Alias Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); Comp; EDM1; EPD1; MED; MGC131819; MGC149768; PSACH; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); putative cartilage oligomeric matrix protein; THBS5; Thrombospondin5; Thrombospondin-5; TSP 5; TSP5
Gene Symbols COMP
Host Species Rabbit
Immunogen E.coli-derived human COMP recombinant protein (Position: Q505-A757).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12845, 1311, 25304
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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