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Invitrogen™ Complement C4d Monoclonal Antibody (10-11)
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Catalog No. PIMA183082
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100 μg
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PIMA183082 100 μg
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Catalog No. PIMA183082 Supplier Invitrogen™ Supplier No. MA183082
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Description

Mouse Monoclonal Antibody

This antibody does not react with bovine, cat, dog, guinea pig, mouse, rabbit, rat or sheep. It has been reported that this antibody works very well on acetone-fixed, frozen renal biopsies. Strong staining is observed in the glomeruli and in some cases the peritubular capillaries. Clone 10-11 has given variable results on formalin-fixed, paraffin-embedded sections. It has been observed that pre-treatment with 88% formic acid for 20 minutes at room temperature is beneficial. Mouse anti Human C4d antibody, clone 10-11 recognizes the secreted protein complement component 4d (C4d).

C4 is a component of the classical complement pathway and is split by activated C1s to C4a and C4b. Together C2a and C4b forms the classical C3 convertase. The molecular mass of C4 is 204 kDa and it consists of 3 subunits: a (97 kDa), b (75 kDa) and g (33 kDa).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Complement C4d
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 10-11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation BBS with <0.1% sodium azide; pH 8.4
Gene C4A
Gene Accession No. P0C0L4, P0C0L5
Gene Alias acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4A; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4D; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4
Gene Symbols C4A, C4B
Host Species Mouse
Immunogen Native protein, from human plasma.
Purification Method Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100293534, 720, 721
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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