Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ Complement Factor Ba Monoclonal Antibody (014III-33.2.4.3)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA528083
Description
This antibody Mouse anti Human Complement Factor B (Ba Fragment) antibody, clone 014III-33.2.4.3 recognizes the 30 kDa Ba fragment of 90 kDa human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change.
CFB is involved in hemolytic uremic syndrome atypical 4 (AHUS4), an atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Disease susceptibility is associated with variations affecting the gene represented in this entry. Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype.
Specifications
Complement Factor Ba | |
Monoclonal | |
1.1 mg/mL | |
BBS with 0.1% sodium azide | |
P00751 | |
CFB | |
Purified human complement factor b. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Western Blot | |
014III-33.2.4.3 | |
Unconjugated | |
CFB | |
AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FB; FBI12; GBG; Glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; Properdin factor B | |
Mouse | |
Protein A | |
RUO | |
629 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction