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Connexin 26 Monoclonal Antibody (CX-1E8), Invitrogen™

Catalog No. PI335800
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100 μg
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Catalog No. Quantity
PI335800 100 μg
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Catalog No. PI335800 Supplier Thermo Scientific Supplier No. 335800

Description

Mouse Monoclonal Antibody

33-5800 was used in the immunofluorescence and western blot analysis to successfully detect Connexin26 in mouse liver sections and homogenate, respectively.

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variables (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Connexin 26
Applications ELISA, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone CX-1E8
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide, pH 7.4
Gene Gjb2
Gene Accession No. P21994, Q00977
Gene Alias AI325222, Cnx26, connexin 26, connexin-26, CX26, CXN-26, DFNA3, DFNA3A, DFNB1, DFNB1A, Gap junction beta-2 protein, gap junction channel protein connexin 26, gap junction membrane channel protein beta 2, gap junction protein beta 2, gap junction protein, beta 2, gap junction protein, beta 2, 26kDa, GJB2, Gjb-2, HID, KID, mutant gap junction protein beta 2, NSRD1, PPK
Gene Symbols Gjb2
Host Species Mouse
Immunogen A 13 amino acid synthetic peptide derived from the C-terminus of the mouse Connexin 26 protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14619, 394266
Target Species Mouse, Rat
Content And Storage -20°C
Form Liquid
Isotype IgG2a κ
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