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Tocris Bioscience™ Covidcil-19
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Catalog No. 748550
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Catalog No. Quantity
74-855-0 50 mg
74-851-0 10 mg
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Catalog No. 74-855-0 Supplier Tocris Bioscience™ Supplier No. 7485/50
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Description

Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency

Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by > 3.5 orders of magnitude.

Specifications

Chemical Name or Material 3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
CAS 1225177-95-6
Quantity 50 mg
Target Antiviral Compounds
Molecular Formula C16H14N4O2
Purity 0.98
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