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Invitrogen™ COX11 Polyclonal Antibody
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Catalog No. PIPA5101304
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Quantity:
100 μL
Catalog No. Quantity
PIPA5101304 100 μL
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Catalog No. PIPA5101304

Supplier: Invitrogen™ PA5101304

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total COX11.

Cytochrome c oxidase (COX) is the terminal enzyme in the electron transfer chain, functioning as a transmembrane proton pump that builds an electrochemical gradient with chemical energy from the reduction of O2. Cytochrome c oxidase assembly protein COX11 is an intracellular mitochondrial membrane protein necessary for the construction of an active COX complex. COX11 contains a single transmembrane helix downstream of the N-terminal, mitochondrial targeting sequence and a C-terminal Cu(I)-binding domain. The assembly of COX requires the delivery of metal cofactors. Along with COX12 and SCO1/2, COX11 acts as a metal ion chaperone necessary for copper insertion into CuA and CuB redox-active copper centers of COX in eukaryotes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX11
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene COX11
Gene Accession No. Q6P8I6, Q9Y6N1
Gene Alias 2010004I09Rik; Cox11; COX11 cytochrome c oxidase copper chaperone; COX11 homolog, cytochrome c oxidase assembly protein; COX11, cytochrome c oxidase copper chaperone; COX11P; cytochrome c oxidase assembly homolog 11; cytochrome c oxidase assembly protein 11; cytochrome c oxidase assembly protein COX11, mitochondrial; cytochrome c oxidase subunit 11
Gene Symbols COX11
Host Species Rabbit
Immunogen A synthesized peptide derived from human COX11(Accession Q9Y6N1), corresponding to amino acid residues S60-S110.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1353, 69802
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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