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Invitrogen™ COX15 Polyclonal Antibody
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Catalog No. PIPA5103383
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100 μL
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PIPA5103383 100 μL
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Catalog No. PIPA5103383 Supplier Invitrogen™ Supplier No. PA5103383
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total COX15.

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family. Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues containing high rates of oxidative phosphorylation including brain, heart and muscle. COX15 defects are the cause of a neurodegenerative disorder known as Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX15
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene COX15
Gene Accession No. Q7KZN9, Q8BJ03
Gene Alias 2900026G05Rik; CEMCOX2; COX15; COX15 cytochrome c oxidase assembly homolog; COX15 homolog, cytochrome c oxidase assembly protein; COX15, cytochrome c oxidase assembly homolog; cytochrome c oxidase assembly homolog 15; cytochrome c oxidase assembly homolog 15 (yeast); cytochrome c oxidase assembly protein 15; cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15
Gene Symbols COX15
Host Species Rabbit
Immunogen A synthesized peptide derived from human COX15(Accession Q7KZN9), corresponding to amino acid residues V271-M321.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1355, 226139, 309391
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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