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Invitrogen™ COX4I2 Polyclonal Antibody
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Catalog No. PIPA518760
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100 μg
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Catalog No. Quantity
PIPA518760 100 μg
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Catalog No. PIPA518760 Supplier Invitrogen™ Supplier No. PA518760
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunbit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix. [Uniprot].
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX4I2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene COX4I2
Gene Accession No. Q96KJ9
Gene Alias COX4I1, COX4I2, COX4I2, cytochrome c oxidase subunit IV isoform 2 lung, COX4, COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2, cytochrome c oxidase subunit IV isoform 2, cytochrome c oxidase subunit IV-like 2
Gene Symbols COX4I2
Host Species Goat
Immunogen Synthetic peptide sequence (RWDYEKKQWKK) corresponding to the C-terminus amino acids of COX4I2 (aa 161-171).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84701
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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