Tocris™ CP 376395 hydrochloride

Potent and selective CRF1 antagonist

Manufacturer: Tocris™ 3212/10

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Catalog No. 32-121-0

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For Research Use Only


    Inhibitors CP 376395 hydrochloride
    Purity >99
    Molecular Weight 362.94
    Quantity 10mg
    Product Type CP 376395 hydrochloride

    Potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000nM for CRF1 and CRF2 receptors respectively). Attenuates CRF-induced activation of the HPA axis in vivo following i.v. administration. Orally active.

    • Chemical Name: N-(1-Ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-4-pyridinamine hydrochloride
    • Formula: C21H30N2O.HCl
    • CAS Number: 1013933-37-3
    • Solubility: Soluble to 50mM in water and to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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