Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ CP 43

Tocris Bioscience™ CP 43
GREENER_CHOICE

Catalog No. p-7145995
Change view
Click to view available options
Quantity:
10 mg
50 mg
Catalog No. Quantity
65-581-0 10 mg
65-585-0 50 mg
2 options
This item is not returnable. View return policy

Catalog No. 65-581-0

Supplier: Tocris Bioscience™ 6558/10

Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Potent TAOK inhibitor

CP 43 is a potent TAO kinase (TAOK) inhibitor (IC50 values are 11 nM/L and 15 nM/L for TAOK1 and TAOK2, respectively). Inhibits TAOK phosphorylation and activation of JNK in vitro. Prolongs duration of mitosis and increases mitotic cell death in the SKBR3 breast cancer cell line. Also reduces tau phopshorylation in cortical neurons at sites associated with neurodegeneration in human tauopathies.

Specifications

Chemical Name or Material N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1′-biphenyl]-4-carboxamide
CAS 850467-66-2
Quantity 10 mg
Molecular Formula C25H24N2O2
Purity 98%
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.