Invitrogen™ CRABP1 Monoclonal Antibody (C-1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3813

Catalog No. MA3813

Description

MA3-813 detects cellular retinoic acid binding protein I (CRABPI) from human, mouse, monkey, feline, bovine, rabbit, rat, turtle and chicken tissues. This antibody does not react with chameleon, goldfish and frog. This antibody does not cross-react with cellular retinol binding protein (CRBP), performic acid oxidized CRBP, interphotoreceptor retinoid binding protein or retinol binding protein. MA3-813 has been successfully used in Western blot, immunohistochemistry and ELISA procedures. By Western blot, this antibody detects a 16 kDa protein representing CRABPI from rat retinal supernatant. Immunohistochemical staining of CRABPI in rat retina with MA3-813 results in its localization to amacrine somata and laminae in the inner plexiform layer. The MA3-813 antigen is oxidized CRABPI from bovine retina.

This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.

Specifications

• Antigen: CRABP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P29762, P40220, P62964, P62965, P62966
• Gene Symbols: CRABP1
• Immunogen: Oxidized CRABPI from bovine retina.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Monkey, Bovine, Feline, Chicken, Reptile
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: C-1
• Conjugate: Unconjugated
• Gene: CRABP1
• Gene Alias: AI326249; cCRABP-I; cellular retinoic acid binding protein 1; cellular retinoic acid binding protein I; cellular retinoic acid binding protein I (CRABP-I) homologue; cellular retinoic acid-binding protein 1; Cellular retinoic acid-binding protein I; cellular retinoic-acid-binding protein; CRABP; Crabp1; Crabp-1; CrabpI; CRABP-I; RBP5; Rbp-5; retinoic acid-binding protein
• Host Species: Mouse
• Purification Method: Affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100338607, 101090941, 12903, 1381, 25061, 282201, 374211
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov