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Cayman Chemical CRAMP140-173mousetrIf 10mg
SDP

Supplier:  Cayman Chemical 3750210 MG

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An inhibitor of the Plk1 polo-box domain (apparent IC50 4.8 UM) selective for the Plk1 PBD over Plk2 and Plk3 PBDs (IC50s 18.7 and 53.9 UM respectively) induces cell cycle arrest at the G2/M phase apoptosis and mislocalization of Plk1 in HeLa cells at 5 10 and 25 UM reduces cell proliferation in a panel of 10 cancer cell lines (EC50s 15-35 UM) reduces tumor growth and induces intratumor apoptosis in an MDA-MB-231 mouse xenograft model at 40 mg/kg

Catalog No. 50-291-7385


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