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CREBL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 180071AP

Catalog No. 50-173-1932


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Description

Description

cAMP response element-binding protein-like-2 was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic maligcies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurrence of CREBL2 deletion in maligcy suggests that CREBL2 may act as a tumor suppressor gene.
Specifications

Specifications

CREBL2
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O60519, Q32M00, Q5BJU6
CREBL2
Rabbit
IgG
150 μL
-20°C
Primary
1389, 232430, 362453
Western Blot
Unconjugated
CREBL2
Liquid
Crebl2
CREBL2 Fusion Protein Ag12504
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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