Invitrogen™ CRG-L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA14325

Catalog No. PA14325

Description

PA1-4325 detects CRG-L2 in human samples. PA1-4325 has been successfully used in Western blotting procedures. The predicted molecular weight is 48 kDa. By Western blot, this antibody detects a protein often above ~50 kDa representing CRG-L2. This protein can form dimers. PA1-4325 immunizing peptide corresponds to amino acid residues 160-176 of human CRG-L2.

CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.

Specifications

• Antigen: CRG-L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gldn
• Gene Alias: cancer related gene - liver 2; cancer-related gene liver 2 protein; Clom; collomin; COLM; colmedin; Crgl2; CRG-L2; Crlg2; FLJ23917; Gldn; Gliomedin; Gliomedin shedded ectodomain; olfactomedin-related protein; UNC-112; UNQ9339/PRO34011
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 342035
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6ZMI3
• Gene Symbols: Gldn
• Immunogen: Synthetic peptide: L(160) V G K A D E K A S E H H S P Q A(176).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG